Depression
Depression
Medically reviewed byGiorgi (Guga) Sikharulidze · MD, PhD — Psychiatrist · Professor · Clinical ResearcherUpdated:
Depression
What is depression?
Depression is a mood disorder in which a person experiences overwhelming feelings of emptiness, sadness, hopelessness and loss of interest. Their surroundings take on a negative tone, everyday activities become unbearably difficult, usual interests diminish and the desire for contact with other people disappears. The ability to experience positive emotions and happiness is lost.
Signs of depression include:
Persistent sadness and hopelessness
Low mood
Anhedonia, or a reduced ability to experience pleasure
Reduced interest
Reduced energy
Insomnia or hypersomnia
Slowed speech
Difficulty maintaining hygiene
Reduced concentration
Low self-esteem
Reduced self-confidence
Self-critical thoughts
Excessive tearfulness
Suicidal thoughts
Reduced ability to work
Psychomotor slowing
Weight changes associated with changes in appetite (gain or loss)
Grief following the loss of a loved one, sadness during a divorce or other difficulties in life are entirely normal. Depression is not simply sadness or a bad mood: its symptoms disrupt every aspect of life, and everyday functioning becomes unbearably difficult.
Depression appears in many forms. Several types can be distinguished, among which a major depressive episode, or clinical depression, is diagnosed most frequently.
Main types of depression:
Major depressive episode (MDD)
A major depressive episode, or “clinical depression,” is a severe mental illness. Diagnosis requires five or more of the signs listed above to persist over time and cause a significant reduction in quality of life, emotional imbalance and psychosocial distress. [2]
Seasonal affective disorder (SAD)
This mood disorder follows a seasonal pattern. Symptoms appear in winter, when temperatures fall and sunlight decreases.
Dysthymia
Dysthymia is a chronic affective disorder with a continuous course. It is often attributed to a person’s character traits and remains undiagnosed for years. In this case, depressive symptoms are milder than in a major depressive episode.
Postpartum depression, or depression after childbirth
Depressive symptoms following childbirth that resolve within no more than two weeks are called “baby blues.” If symptoms continue over time and become more severe, postpartum depression is suspected. Statistically, one in seven women experiences postpartum depression. [1]
Bipolar disorder
Depression is one phase of bipolar disorder. A person experiences extremely polarized, opposing mood states — depression and mania or hypomania — with complete remission (a normal state) in the intervals between them. Bipolarity does not mean frequent mood changes within a day, but alternating prolonged depressive or manic episodes, either following one another continuously or with periods of remission between them.
What can cause depression?
Biological factors: changes in the brain and in neurotransmitter activity
Genetics: depression in family members
Stress and trauma: difficult life events
Hormonal imbalance
Other mental and physical illnesses
Risk factors for depression
Personality traits such as low self-esteem, difficulty being independent, self-criticism and pessimism
Traumatic and stressful factors, physical or sexual abuse, financial difficulties, difficult relationships and the death of a loved one
Relatives with mood disorders or other mental disorders
A history of another mental health difficulty
Alcohol and drug use, including recreational use
Chronic diseases, tumors and disabilities...
Medications that cause depressive symptoms
When should you see a specialist?
Everyone has experienced temporary changes in mood and enjoyment, which is entirely normal. However, depression is not simply a feeling of sadness or low mood. Its symptoms persist and significantly disrupt usual functioning, a person’s thoughts and behavior. Everyday activities become difficult; energy, interest, enjoyment and the ability to work and study decrease...
If you feel that depressive symptoms have not eased over time but have worsened and are disrupting your well-being, see a specialist to receive the necessary help — psychotherapy, medication or a combination of the two.
How is depression treated?
Psychotherapy and medication are effective in treating depression.
See also
→ CBT in the treatment of depression
See also
→ Sleep disturbance and insomnia
→ Borderline personality disorder
References
1. Liu X, Wang S, Wang G. Prevalence and Risk Factors of Postpartum Depression in Women: A Systematic Review and Meta-analysis. J Clin Nurs. 2021;31(19–20):2665–2677. doi:10.1111/jocn.16121
2. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, 5th ed, Text Revision (DSM-5-TR). Washington, DC: APA; 2022.
Frequently asked questions
Sadness or grief during difficulties in life is normal. Depression, however, is not simply sadness or a bad mood: its symptoms persist, disrupt every aspect of life and make everyday functioning unbearably difficult.
The main types of depression include a major depressive episode (clinical depression, the most common), seasonal affective disorder (SAD), dysthymia (chronic and mild), postpartum depression (affecting one in seven women), and the depressive phase of bipolar disorder.
Signs of depression include persistent sadness and hopelessness, low mood, anhedonia (a reduced ability to experience pleasure), reduced interest and energy, sleep disturbance, difficulty concentrating, low self-esteem, self-critical and suicidal thoughts, and changes in appetite and weight.
Psychotherapy and medication are effective in treating depression. Antidepressants, primarily from the SSRI group, form the basis of medication treatment; cognitive behavioral therapy (CBT) and group therapy are leading psychotherapy approaches. When outpatient treatment is ineffective or the condition is severe, a day center is recommended.
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