Marijuana
Marijuana
Medically reviewed byGiorgi (Guga) Sikharulidze · Professor of Psychiatry, MD,PhD · Founder & Clinical Director· Last updated: July 7, 2026
The active substance in cannabis, THC (Delta-9-tetrahydrocannabinol), affects brain neurons and their receptors, which impacts concentration, memory, cognitive functions, coordination, and changes in behavior control.
Marijuana use disrupts mental well-being.
Signs of addiction include:
- Increased tolerance, inability to achieve the usual high
- Irresistible craving
- Long time spent obtaining and using the drug
- Continuous use despite problems created
- Difficulties in fulfilling responsibilities (interpersonal relationships, academic performance, job responsibilities), which contributes to self-critical thoughts and anxiety
- Decreased self-esteem
- Unsuccessful attempts to quit use independently
Withdrawal symptoms include:
- Irritability
- Anxiety
- Sleep disturbances
- Mood swings
- Reduced enthusiasm and energy
- Paranoia
- Psychosis
- Exacerbation of neurotic conditions
Along with the desire to overcome addiction, maintaining a stable mental state and minimizing factors leading to relapse are essential.
Closely related to mental health problems such as:
- Depression
- Anxiety disorders
- Cognitive dysfunction
- Increased risk of suicide
- Psychosis... [1]
References
1. Marconi A, Di Forti M, Lewis CM, Murray RM, Vassos E. Meta-analysis of the Association Between the Level of Cannabis Use and Risk of Psychosis. Schizophr Bull. 2016;42(5):1262–1269. doi:10.1093/schbul/sbw003
Source: NIDA — Cannabis.
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